diff --git a/Marlin/Configuration_adv.h b/Marlin/Configuration_adv.h
index d5780cb9c..462122ebd 100644
--- a/Marlin/Configuration_adv.h
+++ b/Marlin/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/AlephObjects/TAZ4/Configuration_adv.h b/Marlin/example_configurations/AlephObjects/TAZ4/Configuration_adv.h
index 2a2af992d..b88bf1a5c 100644
--- a/Marlin/example_configurations/AlephObjects/TAZ4/Configuration_adv.h
+++ b/Marlin/example_configurations/AlephObjects/TAZ4/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Anet/A6/Configuration_adv.h b/Marlin/example_configurations/Anet/A6/Configuration_adv.h
index b64c77b87..147a6bae0 100644
--- a/Marlin/example_configurations/Anet/A6/Configuration_adv.h
+++ b/Marlin/example_configurations/Anet/A6/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Anet/A8/Configuration_adv.h b/Marlin/example_configurations/Anet/A8/Configuration_adv.h
index 7a27ad869..edd8c834c 100644
--- a/Marlin/example_configurations/Anet/A8/Configuration_adv.h
+++ b/Marlin/example_configurations/Anet/A8/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/BQ/Hephestos/Configuration_adv.h b/Marlin/example_configurations/BQ/Hephestos/Configuration_adv.h
index 4219687a4..a025889e8 100644
--- a/Marlin/example_configurations/BQ/Hephestos/Configuration_adv.h
+++ b/Marlin/example_configurations/BQ/Hephestos/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/BQ/Hephestos_2/Configuration_adv.h b/Marlin/example_configurations/BQ/Hephestos_2/Configuration_adv.h
index 8ee8b7856..7360aec60 100644
--- a/Marlin/example_configurations/BQ/Hephestos_2/Configuration_adv.h
+++ b/Marlin/example_configurations/BQ/Hephestos_2/Configuration_adv.h
@@ -434,8 +434,21 @@
 #define DIGIPOT_MOTOR_CURRENT { 150, 170, 180, 190, 180 }   // Values 0-255 (bq ZUM Mega 3D (default): X = 150 [~1.17A]; Y = 170 [~1.33A]; Z = 180 [~1.41A]; E0 = 190 [~1.49A])
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }      // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/BQ/WITBOX/Configuration_adv.h b/Marlin/example_configurations/BQ/WITBOX/Configuration_adv.h
index 4219687a4..a025889e8 100644
--- a/Marlin/example_configurations/BQ/WITBOX/Configuration_adv.h
+++ b/Marlin/example_configurations/BQ/WITBOX/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Cartesio/Configuration_adv.h b/Marlin/example_configurations/Cartesio/Configuration_adv.h
index cf236db76..81796ef31 100644
--- a/Marlin/example_configurations/Cartesio/Configuration_adv.h
+++ b/Marlin/example_configurations/Cartesio/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Creality/CR-10/Configuration_adv.h b/Marlin/example_configurations/Creality/CR-10/Configuration_adv.h
index 573278c58..f920cc70d 100755
--- a/Marlin/example_configurations/Creality/CR-10/Configuration_adv.h
+++ b/Marlin/example_configurations/Creality/CR-10/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Felix/Configuration_adv.h b/Marlin/example_configurations/Felix/Configuration_adv.h
index 511afd97a..6169acee1 100644
--- a/Marlin/example_configurations/Felix/Configuration_adv.h
+++ b/Marlin/example_configurations/Felix/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/FolgerTech/i3-2020/Configuration_adv.h b/Marlin/example_configurations/FolgerTech/i3-2020/Configuration_adv.h
index ce1f94ac7..eb97f8d78 100644
--- a/Marlin/example_configurations/FolgerTech/i3-2020/Configuration_adv.h
+++ b/Marlin/example_configurations/FolgerTech/i3-2020/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Infitary/i3-M508/Configuration_adv.h b/Marlin/example_configurations/Infitary/i3-M508/Configuration_adv.h
index fc49daf9d..d091a72d7 100644
--- a/Marlin/example_configurations/Infitary/i3-M508/Configuration_adv.h
+++ b/Marlin/example_configurations/Infitary/i3-M508/Configuration_adv.h
@@ -434,8 +434,21 @@
 #define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Malyan/M150/Configuration_adv.h b/Marlin/example_configurations/Malyan/M150/Configuration_adv.h
index 0fb49fef5..03108fa7f 100644
--- a/Marlin/example_configurations/Malyan/M150/Configuration_adv.h
+++ b/Marlin/example_configurations/Malyan/M150/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Micromake/C1/enhanced/Configuration_adv.h b/Marlin/example_configurations/Micromake/C1/enhanced/Configuration_adv.h
index 343284d74..c5328edda 100644
--- a/Marlin/example_configurations/Micromake/C1/enhanced/Configuration_adv.h
+++ b/Marlin/example_configurations/Micromake/C1/enhanced/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/RigidBot/Configuration_adv.h b/Marlin/example_configurations/RigidBot/Configuration_adv.h
index 3b03b218f..de796a4ab 100644
--- a/Marlin/example_configurations/RigidBot/Configuration_adv.h
+++ b/Marlin/example_configurations/RigidBot/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/SCARA/Configuration_adv.h b/Marlin/example_configurations/SCARA/Configuration_adv.h
index bdd6c84a4..0fb51090e 100644
--- a/Marlin/example_configurations/SCARA/Configuration_adv.h
+++ b/Marlin/example_configurations/SCARA/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Sanguinololu/Configuration_adv.h b/Marlin/example_configurations/Sanguinololu/Configuration_adv.h
index 9252ad5ce..ceb4b7648 100644
--- a/Marlin/example_configurations/Sanguinololu/Configuration_adv.h
+++ b/Marlin/example_configurations/Sanguinololu/Configuration_adv.h
@@ -423,8 +423,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/TinyBoy2/Configuration_adv.h b/Marlin/example_configurations/TinyBoy2/Configuration_adv.h
index dee907afe..db5547392 100644
--- a/Marlin/example_configurations/TinyBoy2/Configuration_adv.h
+++ b/Marlin/example_configurations/TinyBoy2/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Velleman/K8200/Configuration_adv.h b/Marlin/example_configurations/Velleman/K8200/Configuration_adv.h
index f917c133a..f8918718e 100644
--- a/Marlin/example_configurations/Velleman/K8200/Configuration_adv.h
+++ b/Marlin/example_configurations/Velleman/K8200/Configuration_adv.h
@@ -447,8 +447,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/Velleman/K8400/Configuration_adv.h b/Marlin/example_configurations/Velleman/K8400/Configuration_adv.h
index 710748a0e..04162f567 100644
--- a/Marlin/example_configurations/Velleman/K8400/Configuration_adv.h
+++ b/Marlin/example_configurations/Velleman/K8400/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h b/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h
index 9cf5b521f..a0f2bcb4c 100644
--- a/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/FLSUN/auto_calibrate/Configuration_adv.h
@@ -436,8 +436,21 @@
 #define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h b/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h
index 5cbe605a9..c3b46261e 100644
--- a/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/FLSUN/kossel_mini/Configuration_adv.h
@@ -436,8 +436,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/delta/generic/Configuration_adv.h b/Marlin/example_configurations/delta/generic/Configuration_adv.h
index 5cbe605a9..c3b46261e 100644
--- a/Marlin/example_configurations/delta/generic/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/generic/Configuration_adv.h
@@ -436,8 +436,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
index 5cbe605a9..c3b46261e 100644
--- a/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
@@ -436,8 +436,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
index 6f9dd7f10..575243724 100644
--- a/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
@@ -441,8 +441,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
index 99fdf9037..cdbef378e 100644
--- a/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
@@ -436,8 +436,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/gCreate/gMax1.5+/Configuration_adv.h b/Marlin/example_configurations/gCreate/gMax1.5+/Configuration_adv.h
index 016e6f835..e17ca0a9a 100644
--- a/Marlin/example_configurations/gCreate/gMax1.5+/Configuration_adv.h
+++ b/Marlin/example_configurations/gCreate/gMax1.5+/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/makibox/Configuration_adv.h b/Marlin/example_configurations/makibox/Configuration_adv.h
index b94f6152d..359a8d9db 100644
--- a/Marlin/example_configurations/makibox/Configuration_adv.h
+++ b/Marlin/example_configurations/makibox/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 4 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS
diff --git a/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h b/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
index 153e385b0..f76d183a6 100644
--- a/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
+++ b/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
@@ -434,8 +434,21 @@
 //#define DIGIPOT_MOTOR_CURRENT { 135,135,135,135,135 }   // Values 0-255 (RAMBO 135 = ~0.75A, 185 = ~1A)
 //#define DAC_MOTOR_CURRENT_DEFAULT { 70, 80, 90, 80 }    // Default drive percent - X, Y, Z, E axis
 
-// Uncomment to enable an I2C based DIGIPOT like on the Azteeg X3 Pro
+// Use an I2C based DIGIPOT (e.g., Azteeg X3 Pro)
 //#define DIGIPOT_I2C
+#if ENABLED(DIGIPOT_I2C) && !defined(DIGIPOT_I2C_ADDRESS_A)
+  /**
+   * Common slave addresses:
+   *
+   *                    A   (A shifted)   B   (B shifted)  IC
+   * Smoothie          0x2C (0x58)       0x2D (0x5A)       MCP4451
+   * AZTEEG_X3_PRO     0x2C (0x58)       0x2E (0x5C)       MCP4451
+   * MIGHTYBOARD_REVE  0x2F (0x5E)                         MCP4018
+   */
+  #define DIGIPOT_I2C_ADDRESS_A 0x2C  // unshifted slave address for first DIGIPOT
+  #define DIGIPOT_I2C_ADDRESS_B 0x2D  // unshifted slave address for second DIGIPOT
+#endif
+
 //#define DIGIPOT_MCP4018          // Requires library from https://github.com/stawel/SlowSoftI2CMaster
 #define DIGIPOT_I2C_NUM_CHANNELS 8 // 5DPRINT: 4     AZTEEG_X3_PRO: 8
 // Actual motor currents in Amps, need as many here as DIGIPOT_I2C_NUM_CHANNELS